[...] And that's where you reach the airtight hatchway: Normal users do not have write permission into the C:\Program Files\Microsoft Office\Office12 directory. You need administrator privileges to create files there. And if you have administrator privileges, then you already pwn the machine. It's not really a vulnerability that you can do anything you want once you pwn the machine. [...]
It rather involved being on the other side of this airtight hatchway: Writing to the application directory (The Old New Thing)
Desativar o UAC no Windows Vista/7/8 ou usar uma conta adminstrativa no XP: arma, pé, mira, tiro.
Windows sem antivírus
Windows Server 2003 como estação de trabalho